BDBM236095 US9365563, G1::US9878991, Compound G1

SMILES OC[C@@H](O)c1cnc(c(Cl)c1)C1(F)CCN(CC1)C(=O)Nc1ccc(cn1)C(F)(F)F

InChI Key InChIKey=IVFZLHSABOTEPQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 236095   

LigandPNGBDBM236095(US9365563, G1 | US9878991, Compound G1)
Affinity DataIC50: 31.3nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM236095(US9365563, G1 | US9878991, Compound G1)
Affinity DataIC50: 16.4nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM236095(US9365563, G1 | US9878991, Compound G1)
Affinity DataIC50: 31.3nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

LigandPNGBDBM236095(US9365563, G1 | US9878991, Compound G1)
Affinity DataIC50: 16.4nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent