BDBM236093 US9365563, E1::US9878991, Compound E1

SMILES CC(C)(C)c1ccc(NC(=O)N2CCC(=CC2)c2ncc(cc2Cl)[C@@H](O)CO)cc1

InChI Key InChIKey=HBPAJYCKDZYFAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236093   

LigandPNGBDBM236093(US9365563, E1 | US9878991, Compound E1)
Affinity DataIC50: 18.5nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM236093(US9365563, E1 | US9878991, Compound E1)
Affinity DataIC50: 18.5nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent