BDBM235736 US9359371, 4

SMILES COc1ccc(CNc2nc(ncc2C(=O)NCc2cnc(C)cn2)N2CC3CC3C2)cc1Cl

InChI Key InChIKey=YTGPPIXKPISAKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235736   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase [537-875](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM235736(US9359371, 4)
Affinity DataIC50: 4.63nMpH: 7.5Assay Description:To a 96-well plate, 20 μL, of 10 μM FL-cGMP as the substrate was added; then 1 μL, of solution of the compound in DMSO or DMSO solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM235736(US9359371, 4)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:To a 96-well plate, 20 μL of 10 μM FL-cGMP as the substrate was added; then 1 μL solution of the compound in DMSO or DMSO solution wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent