BDBM23548 3-Carboxamide-coumarin deriv., 44::8-bromo-6-chloro-2-oxo-N-phenyl-2H-chromene-3-carboxamide

SMILES Clc1cc(Br)c2oc(=O)c(cc2c1)C(=O)Nc1ccccc1

InChI Key InChIKey=IUBMSLQOIUSAFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23548   

TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23548(8-bromo-6-chloro-2-oxo-N-phenyl-2H-chromene-3-carb...)
Affinity DataIC50: 4.40E+3nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Namur

LigandPNGBDBM23548(8-bromo-6-chloro-2-oxo-N-phenyl-2H-chromene-3-carb...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Namur

LigandPNGBDBM23548(8-bromo-6-chloro-2-oxo-N-phenyl-2H-chromene-3-carb...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Namur

LigandPNGBDBM23548(8-bromo-6-chloro-2-oxo-N-phenyl-2H-chromene-3-carb...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of Namur

LigandPNGBDBM23548(8-bromo-6-chloro-2-oxo-N-phenyl-2H-chromene-3-carb...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23548(8-bromo-6-chloro-2-oxo-N-phenyl-2H-chromene-3-carb...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human factor 12a using S-2302 as substrate assessed as para-nitroaniline release preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed