BDBM235377 US10085990, Example 109::US9393245, 109

SMILES COc1cccc2c1ncc1c2n(C2CCN(CC2)S(C)(=O)=O)c(=O)n(-c2ccc3OCOc3c2)c1=O

InChI Key InChIKey=UFKSSXQQJYIWAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235377   

TargetTumor necrosis factor(Human)
Vtv Therapeutics

US Patent
LigandPNGBDBM235377(US9393245, 109 | US10085990, Example 109)
Affinity DataIC50: 8nMT: 2°CAssay Description:Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM235377(US9393245, 109 | US10085990, Example 109)
Affinity DataIC50: 8nMAssay Description:Samples were tested for TNF as per the manufacturer's instructions (TNF ELISA; R&D Systems, Cat #DY210). The samples were serially diluted with P...More data for this Ligand-Target Pair
In DepthDetails
US Patent