BDBM23520 2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanamido}benzoic acid::Biaryl Anthranilide Analogue, 1d

SMILES OC(=O)c1ccccc1NC(=O)CCc1ccc(cc1)-c1ccc(O)cc1Cl

InChI Key InChIKey=IGQQDBCXUBUFTM-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23520   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM23520(2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanami...)
Affinity DataIC50: 4nM EC50:  45nMpH: 7.4 T: 2°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM23520(2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanami...)
Affinity DataEC50:  45nMAssay Description:Displacement of [3H]niacin from GRP109A receptor in presence of 4% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM23520(2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanami...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]niacin from GRP109A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM23520(2-{3-[4-(2-chloro-4-hydroxyphenyl)phenyl]propanami...)
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]-nicotinic acid from N-flag-tagged human HCA2 receptor expressed in HEK293T cell membranes by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed