BDBM233113 N-Cyclohexyl-N'-{4-[6,7-dimethoxy-quinazolin-4-ylamino]phenyl}urea (11j)

SMILES COc1cc2ncnc(Nc3ccc(NC(=O)NC4CCCCC4)cc3)c2cc1OC

InChI Key InChIKey=MWAKSHNGTXXSDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 233113   

TargetEpidermal growth factor receptor(Human)
Universit�� Lille Nord De France

LigandPNGBDBM233113(N-Cyclohexyl-N'-{4-[6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50: 5.13E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Universit�� Lille Nord De France

LigandPNGBDBM233113(N-Cyclohexyl-N'-{4-[6,7-dimethoxy-quinazolin-4...)
Affinity DataIC50: 3.04E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed