BDBM232305 US9346794, 9::US9346794, 9A::US9346794, 9B

SMILES Cc1c(-c2cccc(c2)C(F)(F)F)c(=O)c(cn1Cc1ccc(cc1)C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=NC#N

InChI Key InChIKey=UEGPMTIDRIIUSJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 232305   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM232305(US9346794, 9 | US9346794, 9B | US9346794, 9A)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
Go to US Patent

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM232305(US9346794, 9 | US9346794, 9B | US9346794, 9A)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
Go to US Patent

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM232305(US9346794, 9 | US9346794, 9B | US9346794, 9A)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
Go to US Patent