BDBM23230 2-Oxosuccinic acid::2-oxobutanedioic acid::Oxaloacetate::Oxaloacetic acid::keto-Oxaloacetate

SMILES OC(=O)CC(=O)C(O)=O

InChI Key InChIKey=KHPXUQMNIQBQEV-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23230   

TargetMethyl-accepting chemotaxis protein NahY(Pseudomonas putida (g-Proteobacteria))
Csic

LigandPNGBDBM23230(keto-Oxaloacetate | 2-oxobutanedioic acid | 2-Oxos...)
Affinity DataKd:  2.39E+4nMT: 2°CAssay Description:Measurements were done on a VP-microcalorimeter (MicroCal, Amherst, MA).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase(PBCV-1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM23230(keto-Oxaloacetate | 2-oxobutanedioic acid | 2-Oxos...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM23230(keto-Oxaloacetate | 2-oxobutanedioic acid | 2-Oxos...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM23230(keto-Oxaloacetate | 2-oxobutanedioic acid | 2-Oxos...)
Affinity DataKi:  4.41E+5nMAssay Description:The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 23230   

CellMethyl-accepting chemotaxis protein (McpS)(Pseudomonas putida (g-Proteobacteria))
Csic

SyringePNGBDBM23230(keto-Oxaloacetate | 2-oxobutanedioic acid | 2-Oxos...)
ITC DataΔG°: -6.19kcal/mole −TΔS°: 23.8kcal/mole ΔH°: -30.3kcal/mole logk: 4.18E+4
T: 20.00°C 
In DepthDetails Article
PubMed