BDBM231234 US9346782, 14a::US9346782, 14b::US9346782, 14c
SMILES COc1nc2ccc(cc2c(Cl)c1Cc1ccc(cc1)C(F)(F)F)C(O)(C#C)c1cnc(C)n1C
InChI Key InChIKey=ACZQKZSCRWXAGR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 231234
Affinity DataKd: 60nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
Affinity DataKd: 59nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
Affinity DataKd: 130nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair