BDBM231221 US9346782, 1

SMILES CCCCC(O)(c1cc(C)no1)c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1

InChI Key InChIKey=TZDNTEMAZXWJSW-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231221   

TargetNuclear receptor ROR-gamma [258-518](Artificial Sequence)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM231221(US9346782, 1)
Affinity DataKd:  240nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetNuclear receptor ROR-gamma [258-518,Y502F](Artificial Sequence)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM231221(US9346782, 1)
Affinity DataIC50: 150nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent