BDBM23074 3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]propan-1-one::alpha-ketooxazole, 11f

SMILES O=C(CCc1ccc(Oc2ccccc2)cc1)c1ncc(o1)-c1ccccn1

InChI Key InChIKey=NPLDDPZWNXUZQF-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 23074   

TargetCarboxylic ester hydrolase(Human)
The Scripps Research Institute

LigandPNGBDBM23074(3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataIC50: 200nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23074(3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23074(3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23074(3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataIC50: 200nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA ligase 1(Human)
The Scripps Research Institute

LigandPNGBDBM23074(3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataKi:  3.40nM ΔG°:  -11.5kcal/mole IC50: 2nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23074(3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23074(3-(4-phenoxyphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed