BDBM22987 (5Z,8Z,11Z,14Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]icosa-5,8,11,14-tetraenamide::Arachidonylserotonin::CHEMBL191534::N-arachidonoylserotonin (AA-5-HT)
SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1c[nH]c2ccc(O)cc12
InChI Key InChIKey=QJDNHGXNNRLIGA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 22987
Affinity DataIC50: 8.00E+3nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome
Sapienza University of Rome
Affinity DataIC50: 270nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataEC50: >2.50E+4nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as decrease in intracellular calcium levelMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as inhibition of ADHP to fluorescent resorufin conversion by fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome
Sapienza University of Rome
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRPV1 overexpressed in BEAS-2B cells assessed as calcium flux after 30 mins by Fluo-4 AM fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolase; range=. 5-6 nMMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat brain FAAH using [3H]AEA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair