BDBM226185 Luteolin 7-O-β-D-glucuronide methyl ester (15)

SMILES O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(=O)OCOc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1

InChI Key InChIKey=YIQKLOFYCCOMQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226185   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Catholic University of Daegu

LigandPNGBDBM226185(Luteolin 7-O-β-D-glucuronide methyl ester (15...)
Affinity DataIC50: 4.91E+4nMpH: 6.0Assay Description:PTP1B activity was measured by adding 2mM p-NPP and PTP1B in a 50 mM citrate buffer (pH 6.0, 0.1 M NaCl, 1 mMEDTA, and 1 mM dithiothreitol), with or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetAcetylcholinesterase(Human)
Catholic University of Daegu

LigandPNGBDBM226185(Luteolin 7-O-β-D-glucuronide methyl ester (15...)
Affinity DataIC50: 6.59E+4nMpH: 8.0 T: 2°CAssay Description:Briefly, 140 μL of sodium phosphate buffer (pH 8.0), 20 μL of each tested compound with different concentrations (4, 20, and 100 μM) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details