BDBM226133 1-Benzyl-2,2-diethyl-2,3-dihydro-1H-quinazolin-4-one (2n)

SMILES CCC1(CC)NC(=O)c2ccccc2N1Cc1ccccc1

InChI Key InChIKey=KSOAQXUKCVXSMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226133   

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226133(1-Benzyl-2,2-diethyl-2,3-dihydro-1H-quinazolin-4-o...)
Affinity DataIC50: 1.80E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226133(1-Benzyl-2,2-diethyl-2,3-dihydro-1H-quinazolin-4-o...)
Affinity DataIC50: 4.50E+3nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details