BDBM226128 1,2-Diethyl-2-methyl-2,3-dihydro-1H-quinazolin-4-one (2i)

SMILES CCN1c2ccccc2C(=O)NC1(C)CC

InChI Key InChIKey=IBNJIHIAYDUBEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226128   

TargetAcetylcholinesterase(Electric eel)
University of Sargodha

LigandPNGBDBM226128(1,2-Diethyl-2-methyl-2,3-dihydro-1H-quinazolin-4-o...)
Affinity DataIC50: 2.17E+4nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details

TargetCarboxylic ester hydrolase(Horse)
University of Sargodha

LigandPNGBDBM226128(1,2-Diethyl-2-methyl-2,3-dihydro-1H-quinazolin-4-o...)
Affinity DataIC50: 1.07E+5nMpH: 8.0 T: 2°CAssay Description:AChE and BChE inhibitory assay was carried out by following Ellman's methodology [Ellman et al., Biochem. Pharmacol., 7:88-95] using AChE (Electric e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2017
Entry Details