BDBM225545 GTC000249A

SMILES CN(c1cccc2c1cn[nH]2)c3c(cnc(n3)Nc4ccc5c(c4)S(=O)(=O)NC5)F

InChI Key InChIKey=AKKNJEBKJABIRC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225545   

TargetTyrosine-protein kinase SYK [355-635](Human)
D3R/Abbott

LigandBDBM225545(GTC000249A)Copy SMILESCopy InChI

Affinity DataIC50: 11.6nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/10/2017
Entry Details
Copy Entry DOID3R
PDB3D Structure (crystal)
Copy Rxn URL

TargetTyrosine-protein kinase SYK [355-635](Human)
D3R/Abbott

LigandBDBM225545(GTC000249A)Copy SMILESCopy InChI

Affinity DataIC50: 1.99nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/10/2017
Entry Details
Copy Entry DOID3R
PDB3D Structure (crystal)
Copy Rxn URL