BDBM225267 2-((5-Chloro-2-hydroxyphenyl)amino)-N-(3-(morpholinosulfonyl)phenyl)propanamide (7c)

SMILES CC(Nc1cc(Cl)ccc1O)C(=O)Nc1cccc(c1)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=BVQMYYOWBKUYQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225267   

TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

LigandPNGBDBM225267(2-((5-Chloro-2-hydroxyphenyl)amino)-N-(3-(morpholi...)
Affinity DataIC50: 1.30E+4nMpH: 7.5 T: 2°CAssay Description:The LSD1 screening biochemical assay was performed by Shanghai ChemPartner Co. Ltd and the detailed protocol was shown as followed. The AlphaLISA ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

LigandPNGBDBM225267(2-((5-Chloro-2-hydroxyphenyl)amino)-N-(3-(morpholi...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human LSD1 (158 to end residues) expressed in Escherichia coli preincubated for 15 mins followed by H3K4me2 peptide addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed