BDBM2251 2-Pyridinone derivative 31::3-[ 2-(7-Fluorobenzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridine-2(1H)-thione::5-ethyl-3-[2-(7-fluoro-1,3-benzoxazol-2-yl)ethyl]-6-methyl-1,2-dihydropyridine-2-thione::CHEMBL172583

SMILES CCc1cc(CCc2nc3cccc(F)c3o2)c(=S)[nH]c1C

InChI Key InChIKey=QZOGWNOXUZLRLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2251   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Reserch Laboratories

Curated by ChEMBL
LigandPNGBDBM2251(3-[ 2-(7-Fluorobenzoxazol-2-yl)ethyl]-5-ethyl-6-me...)
Affinity DataIC50: 43nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Merck Reserch Laboratories

Curated by ChEMBL
LigandPNGBDBM2251(3-[ 2-(7-Fluorobenzoxazol-2-yl)ethyl]-5-ethyl-6-me...)
Affinity DataIC50: 43nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed