BDBM224601 US10202383, Example 2(150)::US9321791, 2(150)::US9556175, 2(150)

SMILES CNC(=O)COc1ccccc1C(=O)Cn1c(=O)n(C)c2nc(N3CCC[C@H](N)C3)n(C\C=C\C)c2c1=O

InChI Key InChIKey=LUMINBGDSKHBAQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224601   

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224601(US9556175, 2(150) | US9321791, 2(150) | US10202383...)
Affinity DataIC50: 1nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224601(US9556175, 2(150) | US9321791, 2(150) | US10202383...)
Affinity DataIC50: 1nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224601(US9556175, 2(150) | US9321791, 2(150) | US10202383...)
Affinity DataIC50: 1nMAssay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent