BDBM224581 US10202383, Example 2(37)::US9321791, 2(37)::US9556175, 2(37)

SMILES [#6]-[#7]-[#6](=O)-c1cccc(c1)-[#6](=O)-[#6]-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O

InChI Key InChIKey=MVRXCAMZFHMNQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224581   

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224581(US9556175, 2(37) | US9321791, 2(37) | US10202383, ...)
Affinity DataIC50: 5nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224581(US9556175, 2(37) | US9321791, 2(37) | US10202383, ...)
Affinity DataIC50: 5nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224581(US9556175, 2(37) | US9321791, 2(37) | US10202383, ...)
Affinity DataIC50: 5nMAssay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent