BDBM223071 (E)-N'-(4'-Chlorobenzylidene)isonicotinohydrazide (3a)

SMILES Clc1ccc(\C=N\NC(=O)c2ccncc2)cc1

InChI Key InChIKey=AMDRLZATAWMLKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 223071   

Target5'-nucleotidase(Human)
Quaid-I-Azam University

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50: 1.67E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
Quaid-I-Azam University

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50: 1.08E+3nMpH: 7.4 T: 2°CAssay Description:The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
TargetIntestinal-type alkaline phosphatase(Bovine)
Quaid-I-Azam University

LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50: 670nMpH: 9.8 T: 2°CAssay Description:The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2017
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of Karachi

Curated by ChEMBL
LigandPNGBDBM223071((E)-N'-(4'-Chlorobenzylidene)isonicotinohy...)
Affinity DataIC50: 1.79E+5nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 10 mins followed by substrate addition measured for 15 mins by spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2019
Entry Details Article
PubMed