BDBM223057 US9321721, Example 5::US9321721, Example 8

SMILES NC(=O)\C=C\c1cccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)c1

InChI Key InChIKey=MKFRNUYGBIWLOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223057   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM223057(US9321721, Example 5 | US9321721, Example 8)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM223057(US9321721, Example 5 | US9321721, Example 8)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
Go to US Patent