BDBM222341 (E)-2-(piperidin-1-ylmethyl)-5-(2-(2,2,8-trimethyl-4H-[1,3]-dioxino[4,5-c]pyridin-5-yl)vinyl)phenol (8d)

SMILES Cc1ncc(\C=C\c2ccc(CN3CCCCC3)c(O)c2)c2COC(C)(C)Oc12

InChI Key InChIKey=KEMRSZTUJBXUKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222341   

TargetAcetylcholinesterase(Electric eel)
Sichuan University

LigandPNGBDBM222341((E)-2-(piperidin-1-ylmethyl)-5-(2-(2,2,8-trimethyl...)
Affinity DataIC50: 4.12E+3nMAssay Description:For AChE or BuChE inhibition assays, a reaction mixture (100 mL) containing acetylthiocholine iodide (1 mmol/L, 30 mL) or butyrylthiocholine iodide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sichuan University

LigandPNGBDBM222341((E)-2-(piperidin-1-ylmethyl)-5-(2-(2,2,8-trimethyl...)
Affinity DataIC50: 1.58E+4nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sichuan University

LigandPNGBDBM222341((E)-2-(piperidin-1-ylmethyl)-5-(2-(2,2,8-trimethyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant MAO-B incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed