BDBM22224 2-methyl-3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)propanoic acid::3-arylpropionic acid derivative, 7a

SMILES CC(C)Oc1ccc(cc1C(F)(F)F)-c1nc(no1)-c1ccc(CC(C)C(O)=O)cc1C

InChI Key InChIKey=LCSZAZVGIKVASD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22224   

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

LigandPNGBDBM22224(2-methyl-3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(t...)
Affinity DataEC50:  0.300nMpH: 7.4 T: 2°CAssay Description:EC50s were determined by measuring the binding of [35S]-GTP-gamma-S to S1P receptors expressed in transfected Chinese hamster ovary (CHO) cell membr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

LigandPNGBDBM22224(2-methyl-3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(t...)
Affinity DataEC50:  400nMpH: 7.4 T: 2°CAssay Description:EC50s were determined by measuring the binding of [35S]-GTP-gamma-S to S1P receptors expressed in transfected Chinese hamster ovary (CHO) cell membr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

LigandPNGBDBM22224(2-methyl-3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(t...)
Affinity DataEC50:  9.90nMpH: 7.4 T: 2°CAssay Description:EC50s were determined by measuring the binding of [35S]-GTP-gamma-S to S1P receptors expressed in transfected Chinese hamster ovary (CHO) cell membr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed