BDBM222004 3,5-Bis-(4-chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4,5-dihydro-1H-pyrazole (10j)

SMILES CS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=XOVUEUILNCXCPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222004   

TargetProstaglandin G/H synthase 2(Sheep)
Beni-Suef University

LigandPNGBDBM222004(3,5-Bis-(4-chloro-phenyl)-1-(4-methanesulfonyl-phe...)
Affinity DataIC50: 1.52E+3nMAssay Description:The in vitro inhibition of ovine COX-1 and COX-2 was measured using an enzyme immuno assay (EIA) kit (Cayman Chemical, Ann Arbor, MI, USA) according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

LigandPNGBDBM222004(3,5-Bis-(4-chloro-phenyl)-1-(4-methanesulfonyl-phe...)
Affinity DataIC50: 9.89E+3nMAssay Description:The in vitro inhibition of ovine COX-1 and COX-2 was measured using an enzyme immuno assay (EIA) kit (Cayman Chemical, Ann Arbor, MI, USA) according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed