BDBM221902 US9315463, 12

SMILES COc1cc(NC(=O)OCCN(C)[C@H]2CC[C@@H](CC2)OC(=O)C(O)(c2cccs2)c2cccs2)c(Cl)cc1CNC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=SNXJYSXRLKUBSZ-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 221902   

TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM221902(US9315463, 12)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM221902(US9315463, 12)
Affinity DataIC50: 1.60nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM221902(US9315463, 12)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM221902(US9315463, 12)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human beta2 adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed