BDBM22171 (2R)-1-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazin-1-yl)-3-phenylpropan-2-ol::CHEMBL27490::GBR 12935 Analogue, (R)-5

SMILES O[C@@H](CN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=GJDQYWYMCFMZIM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22171   

TargetSodium-dependent dopamine transporter(Rat)
National Taiwan University

LigandPNGBDBM22171(CHEMBL27490 | (2R)-1-(4-{2-[bis(4-fluorophenyl)met...)
Affinity DataKi:  12nM ΔG°:  -10.0kcal/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Taiwan University

LigandPNGBDBM22171(CHEMBL27490 | (2R)-1-(4-{2-[bis(4-fluorophenyl)met...)
Affinity DataKi:  12nMAssay Description:Binding affinity for dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Taiwan University

LigandPNGBDBM22171(CHEMBL27490 | (2R)-1-(4-{2-[bis(4-fluorophenyl)met...)
Affinity DataKi:  160nM ΔG°:  -8.61kcal/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2008
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Taiwan University

LigandPNGBDBM22171(CHEMBL27490 | (2R)-1-(4-{2-[bis(4-fluorophenyl)met...)
Affinity DataKi:  160nMAssay Description:Binding affinity for serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed