BDBM22056 9-butyl-6-{[(1R)-1-phenylethyl]amino}-9H-purine-2-carbonitrile::Compound 3{4,12}

SMILES CCCCn1cnc2c(N[C@H](C)c3ccccc3)nc(nc12)C#N

InChI Key InChIKey=GNQZKFRLHCGMDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22056   

TargetCathepsin B-like cysteine protease(Trypanosoma brucei)
University of California San Francisco

LigandPNGBDBM22056(9-butyl-6-{[(1R)-1-phenylethyl]amino}-9H-purine-2-...)
Affinity DataIC50: 2.50E+4nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2008
Entry Details Article
PubMed