BDBM220124 US9271961, BMT 4-90

SMILES COc1ccc(c(Nc2ccccc2C(O)=O)c1)N(=O)=O

InChI Key InChIKey=WAXURAGLQIGKCE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 220124   

TargetAldo-keto reductase family 1 member C4(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 2.04E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
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Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 40nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 5.56E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 6.32E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member B1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 4.27E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member B10(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 3.93E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetProstaglandin G/H synthase 1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetProstaglandin G/H synthase 2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent