BDBM220122 US9271961, BMT 3-224

SMILES CC(=O)c1ccc(C(O)=O)c(Nc2ccccc2C(O)=O)c1

InChI Key InChIKey=VNDSZOSZZSPPFX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 220122   

TargetAldo-keto reductase family 1 member C4(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 2.87E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
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Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C3(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 40nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 6.41E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member C1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 3.05E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member B1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 2.77E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetAldo-keto reductase family 1 member B10(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 1.62E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetProstaglandin G/H synthase 1(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
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TargetProstaglandin G/H synthase 2(Human)
University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent