BDBM21952 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-[3-(1H-imidazol-1-yl)propyl]carbamate::Tetrazole-based compound, 18

SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)c1nnnn1CCOC(=O)NCCCn1ccnc1

InChI Key InChIKey=GQUGRYHPMIRJEI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21952   

TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21952(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  45.3nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed