BDBM21948 2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl]-1H-1,2,3,4-tetrazol-1-yl}ethyl N-(4-acetamidobutyl)carbamate::Tetrazole-based compound, 14

SMILES CC(=O)NCCCCNC(=O)OCCn1nnnc1[C@@H](COCc1ccccc1)NC(=O)C(C)(C)N

InChI Key InChIKey=OBOLPKMJYZNIHK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21948   

TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM21948(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  82.5nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed