BDBM218925 US9303033, F4, Table 13A, Compound 14::US9303033, F8, Table 22A, Compound 26

SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(OCC2CC2)c1

InChI Key InChIKey=ILQVTSAQOCHIRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 218925   

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218925(US9303033, F8, Table 22A, Compound 26 | US9303033,...)
Affinity DataIC50: 10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218925(US9303033, F8, Table 22A, Compound 26 | US9303033,...)
Affinity DataIC50: 10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent

TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218925(US9303033, F8, Table 22A, Compound 26 | US9303033,...)
Affinity DataIC50: 2.50E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent

TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218925(US9303033, F8, Table 22A, Compound 26 | US9303033,...)
Affinity DataIC50: 256nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent