BDBM218898 US9303033, Example 33, Table 11, Compound 1

SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(SCc3ccccc3)nc12

InChI Key InChIKey=HKVGQMZATWPSMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218898   

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218898(US9303033, Example 33, Table 11, Compound 1)
Affinity DataIC50: 10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
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TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218898(US9303033, Example 33, Table 11, Compound 1)
Affinity DataIC50: 2.50E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent