BDBM218892 US9303033, Q45, Table 50A, Compound 74::US9303033, X2, Table 9A, Compound 9

SMILES C[C@@H](Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1

InChI Key InChIKey=ISOROGJOHADWEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218892   

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218892(US9303033, Q45, Table 50A, Compound 74 | US9303033...)
Affinity DataIC50: 10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent

TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218892(US9303033, Q45, Table 50A, Compound 74 | US9303033...)
Affinity DataIC50: 1.95E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218892(US9303033, Q45, Table 50A, Compound 74 | US9303033...)
Affinity DataIC50: 100nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
Go to US Patent