BDBM21889 2,9-disubstituted 6-oxopurine, 12m::9-[4-(4-hydroxypiperidin-1-yl)butyl]-2-(phenylamino)-6,9-dihydro-3H-purin-6-one dihydrochloride

SMILES OC1CCN(CCCCn2cnc3c2nc(Nc2ccccc2)[nH]c3=O)CC1

InChI Key InChIKey=YYSHQMGCZBTZSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21889   

TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21889(9-[4-(4-hydroxypiperidin-1-yl)butyl]-2-(phenylamin...)
Affinity DataIC50: 8.20E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Glsynthesis

LigandPNGBDBM21889(9-[4-(4-hydroxypiperidin-1-yl)butyl]-2-(phenylamin...)
Affinity DataIC50: 710nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed