BDBM21872 2,9-disubstituted 6-oxopurine, 6::9-(2-hydroxyethyl)-2-(phenylamino)-6,9-dihydro-3H-purin-6-one::CHEMBL347128

SMILES OCCn1cnc2c1nc(Nc1ccccc1)[nH]c2=O

InChI Key InChIKey=STQPWMSEOLADHB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21872   

TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21872(CHEMBL347128 | 9-(2-hydroxyethyl)-2-(phenylamino)-...)
Affinity DataIC50: 4.40E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
Glsynthesis

LigandPNGBDBM21872(CHEMBL347128 | 9-(2-hydroxyethyl)-2-(phenylamino)-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-1)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM21872(CHEMBL347128 | 9-(2-hydroxyethyl)-2-(phenylamino)-...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HSV-1 thymidine kinase, 1 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidine kinase(HHV-2)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM21872(CHEMBL347128 | 9-(2-hydroxyethyl)-2-(phenylamino)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed