BDBM217977 US10729684, Example 9::US9212182, 645

SMILES COc1cc(C#CC2CCCC2)c(F)cc1-n1c2ccc(cc2ccc1=O)S(=O)(=O)Nc1cccnn1

InChI Key InChIKey=OLFQXWLYHLCGMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 217977   

LigandPNGBDBM217977(US9212182, 645 | US10729684, Example 9)
Affinity DataIC50: 8nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
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LigandPNGBDBM217977(US9212182, 645 | US10729684, Example 9)
Affinity DataIC50: 8.95nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM217977(US9212182, 645 | US10729684, Example 9)
Affinity DataIC50: 19.3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent