BDBM217726 US9212182, 1001::US9212182, 1002::US9212182, 978

SMILES COc1cc(c(F)cc1-n1c2ccc(cc2ncc1=O)S(=O)(=O)Nc1ncccn1)-c1ccc(Cl)c(C)c1

InChI Key InChIKey=AXTYCJDRGGCBIL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 217726   

LigandPNGBDBM217726(US9212182, 978 | US9212182, 1001 | US9212182, 1002)
Affinity DataIC50: 23nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

LigandPNGBDBM217726(US9212182, 978 | US9212182, 1001 | US9212182, 1002)
Affinity DataIC50: 6nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

LigandPNGBDBM217726(US9212182, 978 | US9212182, 1001 | US9212182, 1002)
Affinity DataIC50: 236nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent