BDBM21600 2-{5-chloro-1'-[(5-methyl-3-phenyl-1,2-oxazol-4-yl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2'-dione}acetic acid::Spiro-indolinone analogue, 92

SMILES Cc1onc(c1CN1CCC2(C1=O)C(=O)N(CC(O)=O)c1ccc(Cl)cc21)-c1ccccc1

InChI Key InChIKey=LRFQUBGMBUXPCJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21600   

TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21600(2-{5-chloro-1'-[(5-methyl-3-phenyl-1,2-oxazol-4-yl...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in CHO cells after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM21600(2-{5-chloro-1'-[(5-methyl-3-phenyl-1,2-oxazol-4-yl...)
Affinity DataKi:  2.24E+3nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed