BDBM215345 US9296736, 313::US9593129, Example 313

SMILES C[C@]1(CC(O)=O)C[C@@H]([C@H](N([C@H](CS(=O)(=O)C2CCCC2)C2CC2)C1=O)c1ccc(Cl)cc1)c1cccc(Cl)c1

InChI Key InChIKey=RJVADYQRFCRTCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215345   

LigandPNGBDBM215345(US9296736, 313 | US9593129, Example 313)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandPNGBDBM215345(US9296736, 313 | US9593129, Example 313)
Affinity DataIC50: 0.200nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In DepthDetails
US Patent