BDBM214712 US9296747, Example 7

SMILES COc1ccccc1Nc1ncc2CN(CCc2n1)C(=O)c1cccnc1

InChI Key InChIKey=RYSRPBBVZJAJJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 214712   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM214712(US9296747, Example 7)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2017
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM214712(US9296747, Example 7)
Affinity DataIC50: 244nMpH: 7.4 T: 2°CAssay Description:Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2017
Entry Details
Go to US Patent