BDBM214650 US10688093, Compound 229_0237_0073::US11701353, Compound 229_0237_0073::US9284319, R8::US9730929, Example R8::US9783543, R8

SMILES C(Nc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccncc1

InChI Key InChIKey=AJBOLFIHFBPBBR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 214650   

LigandPNGBDBM214650(US9284319, R8 | US9730929, Example R8 | US9783543,...)
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM214650(US9284319, R8 | US9730929, Example R8 | US9783543,...)
Affinity DataIC50: 34nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214650(US9284319, R8 | US9730929, Example R8 | US9783543,...)
Affinity DataIC50: 23nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214650(US9284319, R8 | US9730929, Example R8 | US9783543,...)
Affinity DataIC50: 34nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM214650(US9284319, R8 | US9730929, Example R8 | US9783543,...)
Affinity DataIC50: 34nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM214650(US9284319, R8 | US9730929, Example R8 | US9783543,...)
Affinity DataIC50: 6.45E+3nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails
US Patent