BDBM213889 5,7-Dichlorokynurenic acid (5,7-DCKA)

SMILES OC(=O)c1cc(=O)c2c(Cl)cc(Cl)cc2[nH]1

InChI Key InChIKey=BGKFPRIGXAVYNX-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 213889   

TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Copenhagen

LigandPNGBDBM213889(5,7-Dichlorokynurenic acid (5,7-DCKA))
Affinity DataKi:  65nM ΔG°:  -9.80kcal/mole IC50: 92nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213889(5,7-Dichlorokynurenic acid (5,7-DCKA))
Affinity DataKi:  3.50E+4nM ΔG°:  -6.07kcal/mole IC50: 9.70E+4nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM213889(5,7-Dichlorokynurenic acid (5,7-DCKA))
Affinity DataKi: >1.50E+5nM ΔG°: >-5.21kcal/mole IC50: 3.00E+5nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed