BDBM213749 US9284299, iCRT5::US9738628, Compound iCRT5

SMILES COc1ccc(\C=C2/SC(=S)N(CCCC(O)=O)C2=O)cc1OC

InChI Key InChIKey=IJWKSBPTJQMUHJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 213749   

TargetCatenin beta-1 [138-686](Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM213749(US9284299, iCRT5 | US9738628, Compound iCRT5)
Affinity DataKi:  4.68E+4nM ΔG°:  -5.90kcal/molepH: 7.4 T: 2°CAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
Go to US Patent

TargetCatenin beta-1 [138-686](Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM213749(US9284299, iCRT5 | US9738628, Compound iCRT5)
Affinity DataKi:  4.68E+4nMAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetCatenin beta-1 [138-686](Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM213749(US9284299, iCRT5 | US9738628, Compound iCRT5)
Affinity DataKi:  8.03E+4nM ΔG°:  -5.58kcal/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
Go to US Patent

TargetCatenin beta-1 [138-686](Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM213749(US9284299, iCRT5 | US9738628, Compound iCRT5)
Affinity DataKi:  8.03E+4nMAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetTranscription factor 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM213749(US9284299, iCRT5 | US9738628, Compound iCRT5)
Affinity DataKi:  8.03E+4nMAssay Description:Inhibition of beta-Catenin/TCF4 (unknown origin) protein-protein interaction assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed