BDBM212645 BDBM212750::US9278954, 1.36

SMILES CC(C(=O)NCC(F)F)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1

InChI Key InChIKey=RSUXEXZLONGJBF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 212645   

TargetAcetyl-CoA carboxylase 2 [129-967](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212645(US9278954, 1.36 | BDBM212750)
Affinity DataIC50: 413nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAcetyl-CoA carboxylase 2 [129-967](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212645(US9278954, 1.36 | BDBM212750)
Affinity DataIC50: 135nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAcetyl-CoA carboxylase 2 [129-967](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212645(US9278954, 1.36 | BDBM212750)
Affinity DataIC50: 872nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In DepthDetails
US Patent