BDBM210943 4-(2-(2-chlorophenyl)-1H-pyrrol-1-yl)-2-(((1r,4r)-4-hydroxycyclohexyl)amino)benzamide (5e)::US10975030, Compound 5e

SMILES NC(=O)c1ccc(cc1NC1CCC(O)CC1)-n1cccc1-c1ccccc1Cl

InChI Key InChIKey=QINPGFULDLKGNQ-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 210943   

TargetEndoplasmin(Human)
The University of Kansas

LigandPNGBDBM210943(4-(2-(2-chlorophenyl)-1H-pyrrol-1-yl)-2-(((1r,4r)-...)
Affinity DataKd:  2.94E+3nMpH: 7.3Assay Description:Assay buffer (25 μL, 20 mM HEPES at pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg mL−1 BGG) was added to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Kansas

LigandPNGBDBM210943(4-(2-(2-chlorophenyl)-1H-pyrrol-1-yl)-2-(((1r,4r)-...)
Affinity DataKd: >1.00E+5nMpH: 7.3Assay Description:Assay buffer (25 μL, 20 mM HEPES at pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg mL−1 BGG) was added to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Kansas

LigandPNGBDBM210943(4-(2-(2-chlorophenyl)-1H-pyrrol-1-yl)-2-(((1r,4r)-...)
Affinity DataKd: >1.00E+5nMAssay Description:Assay buffer (25 μL, 20 mM HEPES pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg/mL BGG) was added to 96-well pl...More data for this Ligand-Target Pair
In DepthDetails
US Patent