BDBM210921 US9273043, C170(r)

SMILES C[C@H](O)[C@@H](O)c1cnc(N2CCN(CC2)C(=O)Nc2nc3cc(C)c(C)cc3s2)c(F)c1

InChI Key InChIKey=AIJMYQIXMWNBRD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 210921   

LigandPNGBDBM210921(US9273043, C170(r))
Affinity DataIC50: 89nMpH: 7.4Assay Description:One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...More data for this Ligand-Target Pair
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Date in BDB:
1/30/2017
Entry Details
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LigandPNGBDBM210921(US9273043, C170(r))
Affinity DataIC50: 32.8nMpH: 7.2 T: 2°CAssay Description:pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...More data for this Ligand-Target Pair
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Date in BDB:
1/30/2017
Entry Details
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LigandPNGBDBM210921(US9273043, C170(r))
Affinity DataIC50: 170nMT: 2°CAssay Description:Briefly, hTRPV1/CHO cells were cultured in growth media in a tissue culture dish at 37° C. in a CO2 incubator. On the day of the assay, culture m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent