BDBM210894 US9273043, A123(e)

SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(Cl)cc2s1)c1ncc(cc1F)[C@@H](O)CO

InChI Key InChIKey=IDHWTEVUUGOISB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210894   

LigandPNGBDBM210894(US9273043, A123(e))
Affinity DataIC50: 11.5nMpH: 7.4Assay Description:One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...More data for this Ligand-Target Pair
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Date in BDB:
1/30/2017
Entry Details
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LigandPNGBDBM210894(US9273043, A123(e))
Affinity DataIC50: 0.400nMpH: 7.2 T: 2°CAssay Description:pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent